Progressive parkinsonism, oculomotor abnormalities and autonomic dysfunction: Clinicopathological case
Identifieur interne : 001452 ( Main/Exploration ); précédent : 001451; suivant : 001453Progressive parkinsonism, oculomotor abnormalities and autonomic dysfunction: Clinicopathological case
Auteurs : Giovanni Fabbrini [Italie] ; Marcello Merello [Argentine] ; Andrew H. Evans [Australie] ; Andrew Lees (neurologue) [Royaume-Uni] ; Janice Holton [Royaume-Uni] ; David R. Williams [Royaume-Uni, Australie]Source :
- Movement Disorders [ 0885-3185 ] ; 2011-02-15.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Autonomic Nervous System Diseases (complications), Autonomic Nervous System Diseases (pathology), Disease Progression, Dysfunction, Female, Humans, Inclusion Bodies (pathology), MSA, Middle Aged, Nervous system diseases, Ocular Motility Disorders (complications), Ocular Motility Disorders (pathology), PSP, Parkinsonian Disorders (complications), Parkinsonian Disorders (pathology), Parkinsonism, Putamen (pathology), clinicopathological case.
- MESH :
Abstract
A 59‐year‐old woman presented with asymmetric parkinsonism that was not‐responsive to Levodopa therapy. She developed early falls, postural instability, and moderately severe autonomic dysfunction. Eye movement abnormalities were reported 2 years after her first symptoms, and she eventually developed anterocollis. Experts discuss the syndromal diagnosis and predict the underlying pathology. The pathological diagnosis is given and clinical learning points are considered. © 2011 Movement Disorder Society
Url:
DOI: 10.1002/mds.23302
Affiliations:
- Argentine, Australie, Italie, Royaume-Uni
- Angleterre, Grand Londres
- Londres
- National Hospital for Neurology and Neurosurgery
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Le document en format XML
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Evans</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Neurology, Royal Melbourne Hospital, Melbourne</wicri:regionArea><wicri:noRegion>Melbourne</wicri:noRegion></affiliation></author><author><name sortKey="Lees, Andrew J" sort="Lees, Andrew J" uniqKey="Lees A" first="Andrew J." last="Lees">Andrew Lees (neurologue)</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Neurology, Reta Lila Weston Institute of Neurological Studies, University College London</wicri:regionArea><wicri:noRegion>University College London</wicri:noRegion><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName>National Hospital for Neurology and Neurosurgery</orgName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Queen Square Brain Bank for Neurological Disorders, University College London</wicri:regionArea><wicri:noRegion>University College London</wicri:noRegion><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName>National Hospital for Neurology and Neurosurgery</orgName></affiliation></author><author><name sortKey="Holton, Janice" sort="Holton, Janice" uniqKey="Holton J" first="Janice" last="Holton">Janice Holton</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Neurology, Reta Lila Weston Institute of Neurological Studies, University College London</wicri:regionArea><wicri:noRegion>University College London</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Queen Square Brain Bank for Neurological Disorders, University College London</wicri:regionArea><wicri:noRegion>University College London</wicri:noRegion></affiliation></author><author><name sortKey="Williams, David R" sort="Williams, David R" uniqKey="Williams D" first="David R." last="Williams">David R. 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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2011-02-15">2011-02-15</date><biblScope unit="vol">26</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="424">424</biblScope><biblScope unit="page" to="429">429</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">ED3955E3C0C98EE8AEC3C90EC497715F134B734E</idno><idno type="DOI">10.1002/mds.23302</idno><idno type="ArticleID">MDS23302</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Autonomic Nervous System Diseases (complications)</term><term>Autonomic Nervous System Diseases (pathology)</term><term>Disease Progression</term><term>Dysfunction</term><term>Female</term><term>Humans</term><term>Inclusion Bodies (pathology)</term><term>MSA</term><term>Middle Aged</term><term>Nervous system diseases</term><term>Ocular Motility Disorders (complications)</term><term>Ocular Motility Disorders (pathology)</term><term>PSP</term><term>Parkinsonian Disorders (complications)</term><term>Parkinsonian Disorders (pathology)</term><term>Parkinsonism</term><term>Putamen (pathology)</term><term>clinicopathological case</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Autonomic Nervous System Diseases</term><term>Ocular Motility Disorders</term><term>Parkinsonian Disorders</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Autonomic Nervous System Diseases</term><term>Inclusion Bodies</term><term>Ocular Motility Disorders</term><term>Parkinsonian Disorders</term><term>Putamen</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Disease Progression</term><term>Female</term><term>Humans</term><term>Middle Aged</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Parkinsonisme</term><term>Pathologie du système nerveux</term><term>Trouble fonctionnel</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A 59‐year‐old woman presented with asymmetric parkinsonism that was not‐responsive to Levodopa therapy. She developed early falls, postural instability, and moderately severe autonomic dysfunction. Eye movement abnormalities were reported 2 years after her first symptoms, and she eventually developed anterocollis. Experts discuss the syndromal diagnosis and predict the underlying pathology. The pathological diagnosis is given and clinical learning points are considered. © 2011 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Argentine</li><li>Australie</li><li>Italie</li><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li></region><settlement><li>Londres</li></settlement><orgName><li>National Hospital for Neurology and Neurosurgery</li></orgName></list><tree><country name="Italie"><noRegion><name sortKey="Fabbrini, Giovanni" sort="Fabbrini, Giovanni" uniqKey="Fabbrini G" first="Giovanni" last="Fabbrini">Giovanni Fabbrini</name></noRegion></country><country name="Argentine"><noRegion><name sortKey="Merello, Marcello" sort="Merello, Marcello" uniqKey="Merello M" first="Marcello" last="Merello">Marcello Merello</name></noRegion></country><country name="Australie"><noRegion><name sortKey="Evans, Andrew H" sort="Evans, Andrew H" uniqKey="Evans A" first="Andrew H." last="Evans">Andrew H. Evans</name></noRegion><name sortKey="Williams, David R" sort="Williams, David R" uniqKey="Williams D" first="David R." last="Williams">David R. Williams</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Lees, Andrew J" sort="Lees, Andrew J" uniqKey="Lees A" first="Andrew J." last="Lees">Andrew Lees (neurologue)</name></region><name sortKey="Holton, Janice" sort="Holton, Janice" uniqKey="Holton J" first="Janice" last="Holton">Janice Holton</name><name sortKey="Holton, Janice" sort="Holton, Janice" uniqKey="Holton J" first="Janice" last="Holton">Janice Holton</name><name sortKey="Lees, Andrew J" sort="Lees, Andrew J" uniqKey="Lees A" first="Andrew J." last="Lees">Andrew Lees (neurologue)</name><name sortKey="Williams, David R" sort="Williams, David R" uniqKey="Williams D" first="David R." last="Williams">David R. Williams</name><name sortKey="Williams, David R" sort="Williams, David R" uniqKey="Williams D" first="David R." last="Williams">David R. 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